User profiles for "author:Oscar Castaño"

Oscar Castaño

Associate Professor at University of Barcelona (UB)
Verified email at ub.edu
Cited by 5142

Neurogenesis and vascularization of the damaged brain using a lactate-releasing biomimetic scaffold

Z Álvarez, O Castaño, AA Castells… - Biomaterials, 2014 - Elsevier
Regenerative medicine strategies to promote recovery following traumatic brain injuries are
currently focused on the use of biomaterials as delivery systems for cells or bioactive …

Engineering Cell‐Derived Matrices: From 3D Models to Advanced Personalized Therapies

G Rubi‐Sans, O Castaño, I Cano… - Advanced Functional …, 2020 - Wiley Online Library
Regenerative medicine and disease models have evolved in recent years from two to three
dimensions, providing in vitro constructs that are more similar to in vivo tissues. By …

Hydrogel co-networks of gelatine methacrylate and poly (ethylene glycol) diacrylate sustain 3D functional in vitro models of intestinal mucosa

A Vila, N Torras, AG Castaño, M García-Díaz… - …, 2020 - iopscience.iop.org
Mounting evidence supports the importance of the intestinal epithelial barrier and its
permeability both in physiological and pathological conditions. Conventional in vitro models …

A microphysiological system combining electrospun fibers and electrical stimulation for the maturation of highly anisotropic cardiac tissue

A López-Canosa, S Perez-Amodio… - …, 2021 - iopscience.iop.org
The creation of cardiac tissue models for preclinical testing is still a non-solved problem in
drug discovery, due to the limitations related to the in vitro replication of cardiac tissue …

Chlorine resistance property improvement of polyamide reverse osmosis membranes through cross-linking degree increment

S Gholami, A Rezvani, V Vatanpour… - Science of The Total …, 2023 - Elsevier
Highly permeable polyamide reverse osmosis (RO) membranes are desirable for reducing
the energy burden and ensuring future water resources in arid and semiarid regions. One …

[HTML][HTML] BBB-on-a-chip with integrated micro-TEER for permeability evaluation of multi-functionalized gold nanorods against Alzheimer's disease

S Palma-Florez, A López-Canosa… - Journal of …, 2023 - Springer
Background The lack of predictive models that mimic the blood–brain barrier (BBB) hinders
the development of effective drugs for neurodegenerative diseases. Animal models behave …

Polymeric composite dressings containing calcium-releasing nanoparticles accelerate wound healing in diabetic mice

S Perez-Amodio, N Rubio, OF Vila… - Advances in Wound …, 2021 - liebertpub.com
Objective: Wound healing is a complex process that involves the interaction between
different cell types and bioactive factors. Impaired wound healing is characterized by a loss …

The effect of the composition of PLA films and lactate release on glial and neuronal maturation and the maintenance of the neuronal progenitor niche

Z Álvarez, MA Mateos-Timoneda, P Hyroššová… - Biomaterials, 2013 - Elsevier
To develop tissue engineering strategies useful for repairing damage in the central nervous
system (CNS) it is essential to design scaffolds that emulate the NSC niche and its tight …

Hierarchically engineered fibrous scaffolds for bone regeneration

N Sachot, O Castaño… - Journal of The …, 2013 - royalsocietypublishing.org
Surface properties of biomaterials play a major role in the governing of cell functionalities. It
is well known that mechanical, chemical and nanotopographic cues, for example, influence …

[HTML][HTML] Microfluidic 3D platform to evaluate endothelial progenitor cell recruitment by bioactive materials

A López-Canosa, S Pérez-Amodio, E Engel… - Acta Biomaterialia, 2022 - Elsevier
Most of the conventional in vitro models to test biomaterial-driven vascularization are too
simplistic to recapitulate the complex interactions taking place in the actual cell …