The American College of Cardiology (ACC) develops a number of policy documents to
provide members with guidance on clinical topics. Although clinical practice guidelines …

Part II of the consensus guidelines updates the recommendations for the periprocedural
management of thrombotic and bleeding risks in patients who require image-guided …

Choosing Wisely® is a medical stewardship and quality improvement initiative led by the
American Board of Internal Medicine Foundation in collaboration with leading medical …

Thrombotic thrombocytopenic purpura (TTP) is a life-threatening systemic illness of abrupt
onset and unknown cause. Proteolysis of the blood-clotting protein von Willebrand factor …

Background The antiplatelet drug clopidogrel is a new thienopyridine derivative whose
mechanism of action and chemical structure are similar to those of ticlopidine. The estimated …

Abstract The American Society for Apheresis (ASFA) Apheresis Applications Committee is
charged with a review and categorization of indications for therapeutic apheresis. Beginning …

Background—Patients experiencing major bleeding while taking vitamin K antagonists
require rapid vitamin K antagonist reversal. We performed a prospective clinical trial to …

Essentials• An international collaboration provides a consensus for clinical definitions.• This
concerns thrombotic microangiopathies and thrombotic thrombocytopenic purpura (TTP).• …

Background Rapid reversal of vitamin K antagonist (VKA)-induced anticoagulation is often
necessary for patients needing urgent surgical or invasive procedures. The optimum means …

The American College of Cardiology (ACC) has a long history of developing documents (eg,
decision pathways, health policy statements, appropriate use criteria) to provide members …