Flow diverters have drastically changed the landscape of intracranial aneurysm treatment
and are now considered first-line therapy for select lesions. Their mechanism of action relies …

Background Concerns over the neurotoxic potential of retained gadolinium in brain tissues
after intravenous gadolinium-based contrast agent (GBCA) administration have led to …

Background Several animal studies have demonstrated that mechanical thrombectomy (MT)
for acute ischemic stroke (AIS) may cause vessel wall injury (VWI). However, the histological …

Background Characterization of acute ischemic stroke (AIS) clots has typically focused on
two-dimensional histological analysis of the thrombus. The three-dimensional (3D) …

Background CT is the most commonly used imaging modality for acute ischemic stroke
evaluation. There is growing interest to use pre-operative imaging to characterize clot …

BACKGROUND: Intracranial dolichoectasia is associated with high morbidity, and its
pathophysiology remains poorly understood. OBJECTIVE: To develop a technique for the …

Background The presence of an outer shell has been recently described as a common
feature of acute ischemic stroke (AIS) thrombi. We performed a systematic review of the …

Background The risk of acute ischemic stroke (AIS) associated with high estrogen states,
including pregnant patients and those using oral contraceptives, has been well documented …

Background: The current evidence supports the benefits of endovascular treatment (EVT) in
acute ischemic stroke (AIS) with large vessel occlusion (LVO). The DAWN and DEFUSE-3 …

The abnormal hemodynamics generated in cerebral aneurysms are believed to play a
central role in progressive wall degradation that can lead to rupture. While elastase induced …