Objectives: This study was designed to establish the incidence, impact, and predictors of
post-transcatheter aortic valve replacement (TAVR) aortic regurgitation (AR). Background …

Transcatheter aortic valve implantation (TAVI) is becoming a reality in the management of
patients with severe aortic stenosis and high or prohibitive risk for standard surgical …

Ventricular septal rupture (VSR) after acute myocardial infarction is increasingly rare in the
percutaneous coronary intervention era but mortality remains high. Prompt diagnosis is key …

Background The use of transcatheter aortic-valve replacement has been shown to reduce
mortality among high-risk patients with aortic stenosis who are not candidates for surgical …

Background Among patients with aortic stenosis who are at intermediate or high risk for
death with surgery, major outcomes are similar with transcatheter aortic-valve replacement …

Background Previous trials have shown that among high-risk patients with aortic stenosis,
survival rates are similar with transcatheter aortic-valve replacement (TAVR) and surgical …

Background Among patients with heart failure who have mitral regurgitation due to left
ventricular dysfunction, the prognosis is poor. Transcatheter mitral-valve repair may improve …

The absence of a robust cell culture model of hepatitis C virus (HCV) infection has severely
limited analysis of the HCV life cycle and the development of effective antivirals and …

Summary Background The Placement of Aortic Transcatheter Valves (PARTNER) trial
showed that mortality at 1 year, 2 years, and 3 years is much the same with transcatheter …

Background Transcatheter aortic-valve replacement (TAVR) is the recommended therapy for
patients with severe aortic stenosis who are not suitable candidates for surgery. The …