User profiles for "author:Sergio Amaro"

Sergio Amaro

Stroke Unit Hospital Clinic Barcelona
Verified email at ictusclinic.com
Cited by 6468

Oral anticoagulant-associated intracerebral hemorrhage

A Cervera, S Amaro, A Chamorro - Journal of neurology, 2012 - Springer
The incidence of oral anticoagulation-associated intracerebral hemorrhage (OAC-ICH) is
growing due to the increasing use of warfarin and the older age of treated patients. Recent …

Acute stroke care is at risk in the era of COVID-19: experience at a comprehensive stroke center in Barcelona

S Rudilosso, C Laredo, V Vera, M Vargas, A Renú… - Stroke, 2020 - Am Heart Assoc
Background and Purpose: The purpose of the study is to analyze how the coronavirus
disease 2019 (COVID-19) pandemic affected acute stroke care in a Comprehensive Stroke …

Effect of intra-arterial alteplase vs placebo following successful thrombectomy on functional outcomes in patients with large vessel occlusion acute ischemic stroke: the …

A Renú, M Millán, L San Román, J Blasco… - Jama, 2022 - jamanetwork.com
Importance It is estimated that only 27% of patients with acute ischemic stroke and large
vessel occlusion who undergo successful reperfusion after mechanical thrombectomy are …

Uric acid administration in patients with acute stroke: a novel approach to neuroprotection

S Amaro, AM Planas, Á Chamorro - Expert Review of …, 2008 - Taylor & Francis
Uric acid (UA) is the end product of purine catabolism in humans and is a powerful
antioxidant whose generation is increased under ischemic conditions. However, both …

Safety and efficacy of uric acid in patients with acute stroke (URICO-ICTUS): a randomised, double-blind phase 2b/3 trial

Á Chamorro, S Amaro, M Castellanos… - The Lancet …, 2014 - thelancet.com
Introduction Uric acid is an antioxidant with neuroprotective effects in experimental models
of stroke. We assessed whether uric acid therapy would improve functional outcomes at 90 …

Catecholamines, infection, and death in acute ischemic stroke

Á Chamorro, S Amaro, M Vargas, V Obach… - Journal of the …, 2007 - Elsevier
Experimental studies have recently suggested that acute ischemia may facilitate the
appearance of fatal infections as part of a brain-induced immunodepression syndrome …

Uric acid reduces brain damage and improves the benefits of rt-PA in a rat model of thromboembolic stroke

E Romanos, AM Planas, S Amaro… - Journal of Cerebral …, 2007 - journals.sagepub.com
Uric acid is a natural antioxidant that protects the brain in a model of transient focal ischemia
in rats. Here we sought to investigate whether uric acid was protective in a model of …

Monocyte subtypes predict clinical course and prognosis in human stroke

X Urra, N Villamor, S Amaro… - Journal of Cerebral …, 2009 - journals.sagepub.com
The number of circulating monocytes increases after stroke. In this study, we assessed the
time course and phenotype of monocyte subsets and their relationship with the clinical …

A pilot study of dual treatment with recombinant tissue plasminogen activator and uric acid in acute ischemic stroke

S Amaro, D Soy, V Obach, A Cervera, AM Planas… - Stroke, 2007 - Am Heart Assoc
Background and Purpose—Uric acid (UA) increases the neuroprotective effects of
recombinant tissue plasminogen activator (rt-PA) in experimental ischemia. In patients with …

Administration of uric acid in the emergency treatment of acute ischemic stroke

L Llull, S Amaro, Á Chamorro - Current neurology and neuroscience …, 2016 - Springer
Oxidative stress is one of the main mechanisms implicated in the pathophysiology of
inflammatory and neurodegenerative diseases of the central nervous system (CNS). Uric …