Mobile stroke care expedites intravenous thrombolysis and endovascular thrombectomy

MT Bender, TK Mattingly, R Rahmani… - Stroke and Vascular …, 2022 - svn.bmj.com
Background The number of mobile stroke programmes has increased with evidence,
showing they expedite intravenous thrombolysis. Outstanding questions include whether …

Catheter based selective hypothermia reduces stroke volume during focal cerebral ischemia in swine

TK Mattingly, LM Denning, KL Siroen… - Journal of …, 2016 - jnis.bmj.com
Background Total body hypothermia is an established neuroprotectant in global cerebral
ischemia. The role of hypothermia in acute ischemic stroke remains uncertain. Selective …

Complications of transradial versus transfemoral access for neuroendovascular procedures: a meta-analysis

D Schartz, SMK Akkipeddi, N Ellens… - Journal of …, 2022 - jnis.bmj.com
Background Transradial access (TRA) has gained increased usage among
neurointerventionalists. However, the overall safety profile of access site complications …

[HTML][HTML] Cold blood perfusion for selective hypothermia in acute ischemic stroke

TK Mattingly, SP Lownie - Brain Circulation, 2019 - journals.lww.com
Hypothermia is the most reliably effective neuroprotectant, and yet systemic complications
limit application. A large body of animal data suggests that hypothermia is effective for focal …

Endovascular therapy is effective for large vessel occlusion despite concurrent cancer

TK Mattingly, JE Risco, JE Burch, R Whyte… - Journal of Stroke and …, 2022 - Elsevier
Objectives Ischemic stroke and concurrent cancer is increasingly recognized. However,
optimal management is uncertain. As mechanical thrombectomy has become the standard …

Endovascular thrombectomy with or without intravenous thrombolysis in acute basilar artery occlusion ischemic stroke: A meta-analysis

GS Kohli, D Schartz, R Whyte, SM Akkipeddi… - Journal of Stroke and …, 2022 - Elsevier
Introduction It is poorly understood if endovascular thrombectomy (EVT) with or without
intravenous thrombolysis (IVT) better facilitates clinical outcomes in patients with acute …

[HTML][HTML] Stroke emboli from patients with atrial fibrillation enriched with neutrophil extracellular traps

SMK Akkipeddi, R Rahmani, D Schartz… - Research and Practice …, 2024 - Elsevier
Background Recent literature has demonstrated remarkable heterogeneity in the
composition of acute ischemic stroke (AIS) emboli, which may impact susceptibility to …

Observation versus intervention for Borden type I intracranial dural arteriovenous fistula: a pooled analysis of 469 patients

D Schartz, R Rahmani, A Gunturi… - Interventional …, 2022 - journals.sagepub.com
Background While it is thought that Borden Type I intracranial dural arteriovenous fistula
(dAVF) have a benign clinical course, their management remains controversial. Methods A …

Noncurative microsurgery for cerebral aneurysms: a systematic review and meta-analysis of wrapping, residual, and recurrence rates

D Schartz, TK Mattingly, R Rahmani, N Ellens… - Journal of …, 2021 - thejns.org
OBJECTIVE Microsurgery for cerebral aneurysms is called definitive, yet some patients
undergo a craniotomy that results in noncurative treatment. Furthermore, the overall rate of …

Histone content, and thus DNA content, is associated with differential in vitro lysis of acute ischemic stroke clots

SMK Akkipeddi, R Rahmani, NR Ellens… - Journal of Thrombosis …, 2024 - Elsevier
Abstract Background Fibrin, von Willebrand factor, and extracellular DNA from neutrophil
extracellular traps all contribute to acute ischemic stroke thrombus integrity. Objectives In …